Hi Christian,
Thanks for your interest in our Syncfusion products.
Syncfusion EssentialStudio v4.2.x.x does not support VisualStudio 2010. We provide the complete support for VisualStudio 2010 from EssentialStudio v8.2.0.18 onwards. Upgrading your project to newer version do not affect the existing behavior of your project.
To migrate your project to newer version of syncfusion assemblies please refer the following KB article.
http://www.syncfusion.com/support/kb/2137/Upgrading-projects-to-a-new-Syncfusion-versionPlease let me know if you have any queries.
Regards,
AnandharmanS