Hi Shridhar,
Are there multiple threads involved in your appilcation? If so, please check the Knowledge Base(KB) article link below.
http://www.syncfusion.com/support/kb/grid/Default.aspx?ToDo=view&questId=78 Intermittant errors can be indications of threading issues. Any calls into the grid must be done on the thread that creates it, and you can use grid.InvokeRequired to check for this.
If you still face the same issues, please send me a working sample so that we may work on it here for you.
Best regards,
Haneef