Hi Julie,
The local culture of the machine could be assigned by using UseCurrentCulture property of the DateTimePickerAdv class. The UseCurrentCulture property sets the system DateTime culture to the DateTimePickerAdv control.
[C#]
this.dateTimePickerAdv1.UseCurrentCulture = true;
this.dateTimePickerAdv1.Format = System.Windows.Forms.DateTimePickerFormat.Custom;
this.dateTimePickerAdv1.CustomFormat = this.dateTimePickerAdv1.Culture.DateTimeFormat.ShortDatePattern.ToString () + " " + this.dateTimePickerAdv1.Culture.DateTimeFormat.ShortTimePattern.ToString();
[Sample]
http://websamples.syncfusion.com/samples/Tools.Windows/F60454/Main.htmPlease try this and let me know if this helps.
Thank you for your interest in Syncfusion products.
Regards,
Murugan P.S