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this.gridGroupingControl1.TableDescriptor.Columns["region"].Appearance.AnyRecordFieldCell.ReadOnly = true;
to make the cell readonly, you can use this handler to prevent teh edit cursor from showing.
private void gridGroupingControl1_TableControlCurrentCellStartEditing(object sender, GridTableControlCancelEventArgs e)
{
GridCurrentCell cc = e.TableControl.CurrentCell;
int field = e.TableControl.TableDescriptor.ColIndexToField(cc.ColIndex);
GridTableCellStyleInfo style = e.TableControl.TableDescriptor.Columns[field].Appearance.AnyRecordFieldCell;
if(style.ReadOnly)
{
e.Inner.Cancel = true;
}
}