Hi Charles,
Thank you for contacting Syncfusion Support.
We have analyzed your query and we have prepared a custom sample in which when you right click on the column headers you will be able to change the column name and when you click any cell, you will get the Current cell’s Column name. Please find the sample link below.
Sample link: http://www.syncfusion.com/downloads/support/forum/119540/ze/Spreadsheet_Demo137253162
Please let us know if you have any queries.
Thanks
Kanimozhi B