Hi Mark ,
You can change the origin of the view according to the location of the nodes in non viewable area in the diagram model. Please refer to the attached sample that demonstrates this completely. In this sample when you checkout the "ViewNode" checkbox, the diagram will automatically scroll down and you can see the Rectangle.
http://websamples.syncfusion.com/samples/Diagram.Windows/F74162/main.htmPlease refer to it and let me know if this helps.
Thanks,
Nagaraj