Hi Rama,
Thank you for your interest in Syncfusion products.
Worksheet.AutofitColumn causes memory corruption I am afraid that I was not able to reproduce the issue. Also I have created a simple sample to test this issue and it is available in the following link:
http://websamples.syncfusion.com/samples/XlsIO.Web/6.1.0.34/I40369/main.htmPlease have a look at the aboave sample and video clip and if still the issue exists, could you please try reproducing it in the above sample and send us the modified sample so that we could sort out the cause of the issue and provide you a solution?
Thanks,
Melba