Hi Mahesh,
Thank you for contacting Syncfusion support.
We analyzed your query and you can handle themouse interactionto child element which is loaded in GridTemplateColumn by setting syncfusion:FocusManagerHelper.WantsKeyInput to True in GridTemplateColumn and setsyncfusion:FocusManagerHelper.FocusedElement to True for enable the focus to child element. Please find the more details regarding GridTemplateColumn focus from the following UG and KB link. . If your requirement defer from this, please share more details regarding your requirement, that would be more helpful for us to serve you.
UG link: http://help.syncfusion.com/UG/winrt/default.htm#!documents/gridtemplatecolumn.htm
KB link: http://www.syncfusion.com/kb/2433/how-to-handle-keyboard-and-mouse-interactions-for-gridtemplatecolumn
Please let us know if you require further assistance.
Thanks,Ashok