Currently SfDataGrid does not render in release mode in Xamarin.Forms.UWP. This is a known Framework issue in the Xamarin.Forms.UWP platform. The custom controls will not render when deploying the application in release mode. Please refer the below Bugzilla link for more details.
The above problem can be resolved by passing the assemblies to include when initializing the Xamarin.Forms in App.xaml.cs in the UWP project as mentioned in the below code example.
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