Yes, It’s possible to differentiate the selection of items in DropDownList using “isInteraction” argument in the select event of DropDownList.
Initialize the DropDownList as follows
Upon selecting the items in the DropDownList, the client side event “select” will be triggered, in that check whether the value of isInteraction argument is true or not. If the value is true, the item has been selected by user(selected through the mouse hover).
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