How do I change the appearance of a single header cell?

//change the appearance of a second header cell
if (e.ColIndex == 2 && e.RowIndex == 0)
{
e.Style.Font.Italic = true;
e.Style.Font.Bold = true;
e.Style.Font.Orientation = 5;
e.Style.TextColor = Color.Red;
}

Private Sub gridDataBoundGrid1_PrepareViewStyleInfo(ByVal sender As Object, ByVal e As Syncfusion.Windows.Forms.Grid.GridPrepareViewStyleInfoEventArgs)
'change the appearance of a second header cell
If e.ColIndex = 2 AndAlso e.RowIndex = 0 Then
e.Style.Font.Italic = True
e.Style.Font.Bold = True
e.Style.Font.Orientation = 5
e.Style.TextColor = Color.Red
End If
End Sub