Hi Ilan,
Thank you for your interest in Syncfusion products.
Yes, it is possible to create such sample using our Essential DocIO in ASP.net.
Please try this which helps you to create sample you expected.
http://www.syncfusion.com/development/uploads/Document_Database_Web_d0f05ef8.zip 1. In this sample while loading it list of documents from the database
2. After select record from the list, if you press read button, then it will open the selected document from the Database
3. If you select an update button, this will open the selected document from DB and update some content and it will update same in the database also.
In the same way you can use Grid instead of list and SQL DB instead of Oledb DB.
Please let me know if you have any other questions.
Best Regards,
Bhuvana